21.01.2026

How to Remove Creases on the Face: Causes and Effective Correction Methods

How to remove creases on the face is a pressing question for many people facing this aesthetic concern. A facial crease is a deep fold or furrow that forms as a result of prolonged exposure of the skin to various factors. Unlike superficial wrinkles, creases affect deeper layers of the dermis and require a professional approach to correction.[1]

What’s the Difference Between a Crease and a Wrinkle?

Understanding the differences between creases and wrinkles is important for choosing the right treatment approach:

Wrinkles:

  • Superficial skin changes
  • Primarily affect the epidermis and upper dermal layers
  • Can be dynamic (appear with facial expressions) or static
  • More easily corrected in early stages[2]

Creases:

  • Deep structural skin changes
  • Affect all layers of the dermis and subcutaneous tissue
  • Always static – visible at rest
  • Require more intensive intervention for correction[1]

What Causes Facial Creases?

Age-Related Changes

The primary cause of crease formation is natural skin aging, which is accompanied by:

  • Loss of skin elasticity and firmness
  • Decreased collagen and elastin synthesis after age 25
  • Skin thinning and reduction of subcutaneous fat
  • Dryness and disruption of the hydrolipid balance[1]

Gravitational Ptosis

Under the influence of gravity, the following occurs:

  • Sagging of facial soft tissues
  • Deformation of facial contours
  • Deepening of natural folds
  • Formation of new creases in areas of greatest tension[3]

Facial Expression Activity

Expression lines eventually transform into creases due to:

  • Constant contractions of facial muscles
  • Formation of persistent folds in areas of active facial expressions
  • Weakening of skin’s supporting structures[2]

Creases on Skin After Sleep

Formation Mechanism

Sleep creases form as a result of:

  • Prolonged pressure of the pillow on facial skin
  • Friction of skin against bedding
  • Improper head position during sleep
  • Insufficient skin elasticity for self-recovery[4]

Characteristics of Morning Creases

How to remove facial creases after sleep depends on their nature:

  • In young people, creases disappear within 30-60 minutes
  • With age, recovery time increases
  • Pillow creases on the face may persist for several hours
  • Regular repetition leads to formation of permanent folds[4]

Crease Localization

Creases around the mouth:

  • Nasolabial folds – from the nose wings to mouth corners
  • Marionette lines – from mouth corners downward
  • Perioral wrinkles – around the mouth
  • Creases on the chin and mentolabial fold area[3]

Other localization zones:

  • Under the eyes – tear trough and malar bags
  • On the forehead – horizontal and vertical creases
  • In the neck and décolletage area
  • Glabellar zone – vertical folds[2]

Prevention of Crease Formation

Proper Sleep

How to remove skin creases on the face related to sleep:

  • Sleep on your back to minimize contact with the pillow
  • Use silk or satin pillowcases
  • Choose orthopedic pillows of proper height
  • Regularly change head position during sleep[4]

Skin Care:

  • Use of moisturizing products
  • Application of creams with retinol and peptides
  • Facial massage to improve circulation
  • Protection from ultraviolet radiation[5]

Healthy Lifestyle:

  • Adequate water consumption
  • Balanced diet with antioxidants
  • Smoking cessation and alcohol limitation
  • Regular physical activity[5]

Can Skin Creases Be Smoothed?

Home Methods

Superficial creases can be reduced through:

  • Intensive skin hydration
  • Massage using oils
  • Facial exercises
  • Application of masks with collagen and hyaluronic acid

Professional Correction Methods

Injectable Techniques:

  • Hyaluronic acid-based fillers to fill creases
  • Biorevitalization and mesotherapy to improve skin quality
  • Botulinum toxin injections to relax facial muscles
  • Collagen therapy to restore the collagen framework[6]

Device-Based Procedures:

  • Laser resurfacing to renew skin surface
  • RF-lifting for tissue tightening
  • Ultrasound facial lifting
  • Microcurrent therapy for muscle stimulation[7]

COLLOST® Collagen Therapy – A Proven Solution

When standard preventive methods prove insufficiently effective and facial creases become well-defined lines and folds, modern collagen therapy comes to the rescue[8].

Injectable collagen administration is widely used in aesthetic cosmetology to compensate for structural protein deficiency in the dermis[8].

COLLOST® preparations, created from natural native collagen (with fully preserved natural molecular structure) of animal origin, not only restore skin structure but also activate the function of fibroblasts – cells responsible for producing the body’s own collagen.[9]This provides the body with necessary building material for natural synthesis of collagen fibers.

Thus, COLLOST® acts on three levels:

  • Forms a new skin framework
  • Triggers synthesis of the body’s own collagen
  • Serves as building material for regeneration

After a course of COLLOST® subcutaneous injections, skin acquires greater firmness, becomes smooth and radiant, and deep creases and folds are significantly smoothed and become less noticeable.[9]

COLLOST® contains the maximum collagen concentration on the global market — 15%.

COLLOST® is available as micronized powder COLLOST® micro and as gel COLLOST® gel 7% and COLLOST® gel 15%. The preparations can be injected into the upper and lower eyelid skin up to the lash line.

COLLOST® micro is based on unique patented PoliONICol® and MicronONIC® technologies.

PoliONICol® technology (Polianionic Outstanding Native Innovative Collagen) enhances the hydrating properties of collagen.

MicronONIC® microstructuring technology (Micronized Outstanding Native Innovative Collagen) allows formation of material consisting of interwoven thread-like biomimetic particles. Capillary spaces between microfibers attract and retain water, facilitate cell penetration into the material’s depth. The fibrous structure of microparticles serves as both a biological and mechanical activator of the regeneration process, stimulating neocollagenogenesis.

Advantages of Collagen Therapy

  • Naturalness – use of natural collagen
  • Safety – minimal risk of allergic reactions[11]
  • Long-term effect – stimulation of the body’s own collagenogenesis

Features of Crease Correction in Different Zones

Nasolabial Creases

Nasolabial creases on the face require a combined approach:

  • Correction of midface volume
  • Filling folds with fillers
  • Stimulation of collagen production
  • Improvement of skin tone[3]

Periorbital Zone

Under-eye creases are corrected with particular caution:

  • Use of special injection techniques
  • Low-viscosity preparations
  • Minimal volumes to prevent swelling
  • Targeted correction of problem areas[2]

Forehead Area

Forehead creases often combine with brow ptosis:

  • Correction of horizontal folds
  • Relaxation of facial muscles
  • Upper face tissue lifting
  • Volume restoration in temporal areas[7]

Contraindications to Crease Correction

Absolute Contraindications:

  • Acute inflammatory processes on facial skin
  • Oncological diseases
  • Blood clotting disorders
  • Pregnancy and lactation period[10]

Relative Contraindications:

  • Tendency to form keloid scars
  • Taking anticoagulants
  • Exacerbation of chronic diseases
  • Menstruation in women

Treatment Prognosis and Results

Expected Effects

  • Significant smoothing of deep creases
  • Improvement of skin texture and tone
  • Restoration of clear facial contours
  • Overall rejuvenation and fresh appearance

Duration of Results

  • Fillers – 8-18 months depending on zone
  • Collagen therapy – up to 12 months with cumulative effect
  • Device-based procedures – 6-12 months
  • Combined methods – up to 2 years with proper care

Recommendations for Maintaining Results

Home Care:

  • Regular use of moisturizing products
  • Application of SPF 30+ sunscreen
  • Facial massage to maintain tone
  • Use of cosmetics with active ingredients

Professional Support:

  • Maintenance procedures every 6-12 months
  • Regular consultations with cosmetologist
  • Adjustment of care program as needed
  • Preventive device-based procedures

Innovative Crease Correction Methods

Combined Protocols

Modern cosmetology offers comprehensive programs:

  • Combination of injectable and device-based methods
  • Staged correction with intervals
  • Individual selection of preparations and techniques
  • Results monitoring at each stage

Personalized Approach:

  • Consideration of individual skin characteristics
  • Analysis of patient’s lifestyle and habits
  • Program adjustment depending on results
  • Long-term planning of maintenance procedures

Conclusion

How to remove creases on the face? Modern aesthetic medicine offers a wide range of correction methods, from preventive measures to innovative injection technologies. The key to success is timely consultation with a specialist, proper diagnosis of crease formation causes, and selection of an optimal treatment program.

Collagen therapy with COLLOST® preparations represents a modern solution for correcting facial skin creases, providing not only immediate aesthetic effect but also long-term improvement in skin quality. It’s important to remember that the best results are achieved with a comprehensive approach, including professional procedures, proper home care, and a healthy lifestyle.

References

  1. Korolkova T.N. Human aging in light of modern theories / T.N. Korolkova // Collection of articles of NPO of cosmetologists of St. Petersburg. – Issue 2. – 2001. – pp. 6–16.
  2. Meshchaninov V.N. Metabolism of cellular structures during aging and stress / V.N. Meshchaninov, D.L. Shcherbakov, V.A. Lukash. — Yekaterinburg: USMU Publishing House, 2017. — 308 p.
  3. Hee K.C., Seo K.K., Lee H.-K., Kim C. Clinical anatomy of the face as applied to contour plasty using fillers and botulinum toxin / Ed. by I.E. Khrustaleva. – Moscow, 2022. – 192 p.
  4. Adler Y. What skin hides. M.: Eksmo, 2017 (electronic version from OOO «Publishing House «E»», 2017).
  5. Goncharova T.A. Beauty secrets. M.: Kron-press, 1997.
  6. Demyanenko I.A., Shishkina A.V., Kalmykova N.V. Collagen-based injectable implants for use in cosmetology and aesthetic medicine: review of preparations presented on the Russian market // Injectable Cosmetology. – 2020. – 3. – pp. 32–39.
  7. Barinova A.N., Ponomarev I.V. Modern device-based methods in aesthetic medicine // Plastic Surgery and Cosmetology. – 2018. – 3. – pp. 15–24.
  8. Kapuler O.M. Theoretical aspects and clinical principles of collagen therapy in cosmetology / O.M. Kapuler // Injectable Methods in Cosmetology. — 2013. — 1. — pp. 100-109.
  9. Application of COLLOST® gel 7% collagen complex for correction of involutional-depressive changes of facial skin, neck, décolletage, shoulders: methodological recommendations / O.S. Panova. — M., 2014. — 15 p.
  10. Olisova O.Yu., Teplyuk N.P. Contraindications to cosmetic procedures // Russian Journal of Skin and Venereal Diseases. – 2019. – 22(1). – pp. 67–74.
  11. Patent 2353397. Russian Federation. Bioresorbable collagen matrix, method for its production and application / A.A. Safoyan, S.V. Nesterenko, V.G. Nesterenko, N.Yu. Alekseeva. Applicant CJSC «BioFARMAKHOLDING» – 2007113962/15; filed 13.04.2007; published 27.10.2008, Bull. 30.

 

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