COLLOST® - the unique collagen material provides the main biological resources of the tissue for the synthesis of new collagen.
The product contains native type I collagen, which is as close as possible to human collagen in composition and structure.
About the product
Collagen is the basis of healthy skin
In youth, collagen turnover is ~6 kg per year
After age 25–30, collagen content in the skin declines by 20% every 10 years
Collagen restorationby middle age, drops to ~3 kg
COLLOST® starts the process of regeneration and renewal of skin cells, stimulating the production of new collagen at 3 levels:
Structural scaffold for new collagen framework
Triggers endogenous collagen synthesis
Provides building blocks and combats free radicals
It stimulates the production of its own collagen, providing a more natural and sustainable rejuvenation result
It contains the maximum concentration of collagen on the world market up to 15%
It allows you to work with thinned skin of the eyelids (up to the ciliary edge), neck, and hands
The unique technologies in the composition increase the firmness and elasticity of the skin without causing puffiness
Provides a long-lasting effect of the procedure (up to 2 years)
COLLOST® has low immunotropic and allergenic activity
| Parameter | Cattle | Horse | Marine (fish, invertebrates) | Recombinant |
|---|---|---|---|---|
| Identified type of collagen | I, III | I (Sometimes III) | I (Sometimes II, IV) | I, III configurable |
| Hydroxyproline (% by weight) | 12.5–13.4% | 12.5–13.4% | 7.1–11.3% | 0-13.4% (depending on the producer) |
| Proline (% of protein) | 12% | 12% | 8-10% | 12% |
| Denaturation temperature (Tm) | 38–41 °C | 37–38.5 °C | 20–30 °C | 0-13.4% (depending on the producer) |
| Solubility (pH7.4, 25 °C) | Average | Average | Very high | Medium/high |
| Stability under physiological conditions | Tall | Tall | Medium/low | Medium/high |
The technology allows you to enhance the hydrating properties of collagen.
It is used to increase the biocompatibility of the material.
COLLOST® is an injectable preparation based on native type I collagen of animal origin, which restructures the skin framework, triggers the synthesis of its own collagen and is a building material for regeneration.
COLLOST® is used in cosmetology to improve the quality of the skin of the face and body, correct scars, including striae, as well as in the treatment of age-related skin changes. It is produced in Russia by BioPHARMAHOLDING, LLC.
It is available in several forms:
COLLOST® gel 7% and 15% — ready-made gel;
COLLOST® micro is a micronized powder.
COLLOST® is manufactured using a unique patented technology that preserves the triple-helix structure of the native collagen molecules (meaning its spatial form remains intact). Thanks to this structure, it acts as a matrix for targeted local tissue regeneration, ensuring a pronounced biological effect.
COLLOST® is an injectable preparation with a maximum collagen content ranging from 3% to 15%.
COLLOST® contains native type I collagen of animal origin (bovine collagen), which has undergone multi-stage purification and strict safety control. It holds a Halal certificate.
Stimulation of collagen synthesis begins immediately after the injection. According to normal physiology, a minimum of two weeks is required for the "repair" of collagen fibers.
The first result after the COLLOST® micro procedure can be seen in 3-5 days, while the result after COLLOST® gels can be assessed two weeks after the procedure. The effect of collagen therapy increases over a period of 2-3 months.
Botulinum toxin injections help to relax the facial muscles, which reduces the appearance of wrinkles. When combined with collagen injections, the skin not only becomes smoother but also gains increased firmness and elasticity due to the restoration of its structure.
Plasmapheresis utilizes the patient's own plasma, enriched with platelets, to stimulate skin regeneration. When combined with collagen injections, this approach enhances regenerative processes, improving skin texture and tone.
Collagen therapy effectively complements hardware techniques, serving as the preferred procedure for preparing the skin for device-based treatments. It enhances results, promotes accelerated rehabilitation following traumatic procedures, and contributes to achieving a more pronounced effect.
Fillers, such as hyaluronic acid, are used to fill deep wrinkles and enhance volume in specific areas of the face. Collagen injections can amplify the effects of this procedure by improving skin structure and preventing further aging.
This procedure involves injecting hyaluronic acid along with nutrient cocktails containing vitamins, amino acids, and other active compounds into the skin. When combined with collagen injections, mesotherapy enhances rejuvenation effects, improves skin texture and tone, while restoring the skin's natural barrier and providing deep hydration.
Write to us and our specialists respond as soon as possible
